Drug Design and/or Synthesis

Novel antibactirial agent for treatment of infections caused by S. aureus including MRSA.

KEYWORDS 

Enoyl-ACP reductase l Bacterial Fatty Acid Biosynthesis l Antibacterial FabI l Pyridone Inhibitor

Our novel 18F-labeled GSK3b inhibitors can cross blood brain barrier

KEYWORDS 

PET Tracers l Neurological disorders l imaging l glycogen synthase kinase

An elegant approach to reduce the loss of efficacy of an anticancer drug in its conjugated form.

KEYWORDS 

Trazine l Linker l Drug delivery l Tumor targeting l Cancer imaging

Our PEX-9 inhibitors selectively inhibit cell migration thereby reducing cell invasion that causes metastasis

KEYWORDS 

MMP9 inhibitors l PEX domain inhibitors l anti-cancer l anti-metastatic l CAM assay

The technology relates to the anticancer prodrugs that can be activated by the two key enzymes overexpressed in metastatic cancer cells.

KEYWORDS 

Anticancer drug therapy l Chemotherapeutic prodrugs l Cancer

Our first-in-class, broad spectrum viral inhibitors demonstrated high specificity and efficacy in inhibiting viral production by targeting a host cellular factor

KEYWORDS 

Viral inhibitors

KEYWORDS 

miRNA, cancer therapeutic, colon cancer, small molecule

Efficient Nebulizer chamber which allows control of the inhaled mass of the drug, the need for breath actuation, the breathing pattern, and the particle distribution.

KEYWORDS 

Particle distribution, Nebulizer, Humidity, Ultrasonic mesh

Meathod for minimizing the rate of occurances of Catheter Associated Urinary Tract Infections in patients using visible light.

KEYWORDS 

Urinary Tract Infections, UTI, Catheters, Blue light, Infectious disease, Drug resistance

Enables the creation of long length polymers that have a low distribution of molecular mass.

KEYWORDS 

ROMP l Grubbs catalyst l Alkene isomerization l Ruthenium

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